{"id":26546,"date":"2025-12-19T10:55:38","date_gmt":"2025-12-19T09:55:38","guid":{"rendered":"https:\/\/dev8.id-interactive.fr\/new_unither\/la-technologie-sol-gel\/"},"modified":"2026-02-03T15:52:29","modified_gmt":"2026-02-03T14:52:29","slug":"la-technologie-sol-gel","status":"publish","type":"post","link":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/la-technologie-sol-gel\/","title":{"rendered":"La technologie Sol-Gel"},"content":{"rendered":"\r\n<div class=\"wp-block-image\">\r\n<figure class=\"alignleft size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1664\" src=\"https:\/\/www.unither-pharma.fr\/wp-content\/uploads\/2020\/08\/iStock-1207459706-700x525.jpg\" alt=\"\" width=\"207\" height=\"155\" \/><\/figure>\r\n<\/div>\r\n\r\n\r\n\r\n\r\n\r\n<h2><strong>Unither soutient l\u2019innovation au service du patient.<\/strong><\/h2>\r\n\r\n\r\n\r\n<p>C\u2019est dans cette optique que nous collaborons avec le CNRS, l\u2019Universit\u00e9 Paris Descartes et l\u2019Assistance Publique \u2013 H\u00f4pitaux de Paris notamment l\u2019Agence G\u00e9n\u00e9rale des Equipements et Produits de Sant\u00e9 (AGEPS) sur la technologie Sol-Gel depuis 2012.<\/p>\r\n\r\n\r\n\r\n<p>Jusqu\u2019\u00e0 pr\u00e9sent 6 publications scientifiques internationales d\u00e9di\u00e9es \u00e0 la technologie Sol-Gel ont \u00e9t\u00e9 publi\u00e9es.<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-table is-style-stripes\">\r\n<table>\r\n<tbody>\r\n<tr>\r\n<td><strong>2014<\/strong><\/td>\r\n<td>\u00a0<\/td>\r\n<td>Influence of additives on a thermosensitive hydrogel for buccal deliveryof salbutamol: Relation Between micellization, gelation, mechanic and release properties<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>2015<\/strong><\/td>\r\n<td>\u00a0<\/td>\r\n<td>Poloxamer bioadhesive hydrogel for buccal drug delivery: Cytotoxicity and trans<br \/>epithelial permeability evaluations using TR146 human buccal epithelial cell line<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>2016<\/strong><\/td>\r\n<td>\u00a0<\/td>\r\n<td>In\u00a0vitro and in vivo evaluation of in situ gelling systems for sustained topical ophthalmic delivery: state of the art and beyond<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>2017<\/strong><\/td>\r\n<td>\u00a0<\/td>\r\n<td><a href=\"https:\/\/hal.archives-ouvertes.fr\/hal-02123148\/document\">Cyanine derivative as a suitable marker for thermosensitive in situ gelling delivery systems: In vitro and in vivo validation of a sustained buccal drug delivery<\/a><\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>2019<\/strong><\/td>\r\n<td>\u00a0<\/td>\r\n<td>Novel in situ gelling ophthalmic drug delivery system based on gellan gum and hydroxyethylcellulose: Innovative rheological characterization, in vitro and in vivo evidence of a sustained precorneal retention time<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>2020<\/strong><\/td>\r\n<td>\u00a0<\/td>\r\n<td><a href=\"https:\/\/hal.sorbonne-universite.fr\/hal-02798293\/document\">In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics<\/a><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/figure>\r\n\r\n\r\n\r\n<h2 class=\"wp-block-heading\">L&rsquo;usage Ophthalmique<\/h2>\r\n\r\n\r\n\r\n<p>Unither n\u2019a cess\u00e9 de travailler et investir ses efforts dans la recherche et le d\u00e9veloppement ophtalmologique, avec pour but principal de faciliter la vie des patients.<\/p>\r\n\r\n\r\n\r\n<p>Le savoir-faire ophtalmique d\u2019Unither se traduit \u00e0 travers des d\u00e9veloppements sur les\u00a0<a href=\"https:\/\/www.unither-pharma.fr\/nos-sites\/\">sites<\/a>\u00a0de Coutances et Amiens, ainsi que les laboratoires de Bordeaux (France) et Wuhan (Chine), mais aussi les travaux de recherche sur la technologie Sol-Gel men\u00e9s depuis 2012 (6 publications scientifiques internationales), initi\u00e9s par Ni Zeng, Responsable du D\u00e9veloppement pour la Chine, et repris par la suite par Pierre-Louis Destruel, ancien Charg\u00e9 de d\u00e9veloppement pour la Chine.<\/p>\r\n\r\n\r\n\r\n<p>Cela nous a demand\u00e9 plus de 3 ans de recherches afin de d\u00e9livrer les r\u00e9sultats finaux sur\u00a0<strong>le Sol Gel mydriatique,<\/strong>\u00a0<strong>un nouveau gel ophtalmique actif in situ pour optimiser l\u2019induction de la mydriase diagnostique et pr\u00e9 op\u00e9ratoire<\/strong>. Ce travail a \u00e9t\u00e9 r\u00e9alis\u00e9 conjointement avec les \u00e9quipes d\u2019Unither et celles de l\u2019AGEPS \u00ab\u00a0l\u2019Agence G\u00e9n\u00e9rale des Equipements et\u00a0<a href=\"https:\/\/www.unither-pharma.fr\/produits\/liste-produits\/\">Produits<\/a>\u00a0de Sant\u00e9, AP-HP\u00a0\u00bb, et l\u2019\u00a0\u00bbUnit\u00e9 de\u00a0<a href=\"https:\/\/www.unither-pharma.fr\/technologies\/\">technologies<\/a>\u00a0chimiques et biologiques pour la sant\u00e9, Universit\u00e9 de Paris, CNRS, INSERM, Facult\u00e9 de Pharmacie\u00a0\u00bb.<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-4-3 wp-has-aspect-ratio\">\r\n<div class=\"wp-block-embed__wrapper\">https:\/\/www.youtube.com\/watch?v=mvPvz17-lCg<\/div>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>Si vous souhaitez en savoir plus et recevoir l&rsquo;une des publications vous pouvez envoyer votre demande par mail \u00e0\u00a0<a href=\"mailto:unither@unither-pharma.com\">unither@unither-pharma.com<\/a>\u00a0<\/p>\r\n\r\n\r\n\r\n<div class=\"wp-block-spacer\" style=\"height: 47px;\" aria-hidden=\"true\">\u00a0<\/div>\r\n\r\n\r\n\r\n<p>&nbsp;<\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>Unither soutient l\u2019innovation au service du patient. C\u2019est dans cette optique que nous collaborons avec le CNRS, l\u2019Universit\u00e9 Paris Descartes et l\u2019Assistance Publique \u2013 H\u00f4pitaux de Paris notamment l\u2019Agence G\u00e9n\u00e9rale des Equipements et Produits de Sant\u00e9 (AGEPS) sur la technologie Sol-Gel depuis 2012. Jusqu\u2019\u00e0 pr\u00e9sent 6 publications scientifiques internationales d\u00e9di\u00e9es \u00e0 la technologie Sol-Gel ont [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1684,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-26546","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/posts\/26546","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/comments?post=26546"}],"version-history":[{"count":2,"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/posts\/26546\/revisions"}],"predecessor-version":[{"id":26907,"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/posts\/26546\/revisions\/26907"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/media\/1684"}],"wp:attachment":[{"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/media?parent=26546"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/categories?post=26546"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dev8.id-interactive.fr\/new_unither\/fr\/wp-json\/wp\/v2\/tags?post=26546"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}